The other day I read an article from a woodturner reporting that after rough-turning a piece of spalted timber (can't remember the species) without protection, a few days later he ended up in hospital and almost died from a fungal infection of his lungs. Took some serious efforts from the docs to keep him alive and get him back onto his feet.
Having said that, I think this was a very exceptional case. It is certainly true that we are surrounded by spores everywhere, and it's therefore safe to assume that our bodies can handle most of them quite easily. I still wouldn't recommend ingesting spalted timber if it can be avoided.
Now, coming back to the original post: using oak for a mortar and pestle. I am not quite sure why Les was so aghast. OK, oak is an open grained wood, which makes it less than ideal for this purpose. And most of it has got loads of tannin, which will impart a nice vinegary taste onto whatever your pounding the hell out of. But other than that, it should be fine. Wouldn't be my choice, to be sure, but the customer gets what the customer wants.